Research & Publications

Research Grants

• A pilot study investigating the use of vaginal hyaluronic acid to enhance innate immunity against post-menopausal recurrent urinary tract infection. The Urology Foundation (TUF) 2018-20: £99,783 ($130,000)

• BETTER Bladders: Bladder Epithelial Therapy Through Epigenetic Rejuvenation. IMPRESS, Next Generation Technologies for Incontinence 2016-17: £50,042 ($65,000)

• ALternative To prophylactic Antibiotics for the treatment of Recurrent urinary tract infections in women – ALTAR (Co-Investigator). UK National Institute for Health Research (NIHR) 2016-19: £956,990  ($1,450,000)

• Dissecting the role of the Dectin-1 Receptor in the Innate Defences of the Uro-genital Tract (Co-Investigator). Dr William Edmund Harker Foundation 2014-18: £80,000  ($120,000)

• Recurrent Urinary Tract Infection: oestrogen and the epithelial defences of the urinary tract (Co-Investigator). UK Medical Research Council (MRC) 2012-16: £80,000  ($120,000)

• Beyond Estrogen Treatment: Unlocking the Ability of Beta Defensin 2 to Prevent Urinary Tract Infection in Post-menopausal Women (Co-Investigator). Wellbeing of Women 2011-14: £151,417  ($250,000)

• An Investigation into the Expression and Localisation of Toll-Like Receptors and Beta-Defensin Antimicrobial Peptides in Chronically Infected Kidneys (Co-Investigator). Kidney Research UK 2012-13: £5,000  ($7,500)

• Antimicrobial Peptides and Interstitial Cystitis (Co-Investigator). Cystitis and Overactive Bladder Foundation 2011-13: £20,000 ($30,000)

• The Role of Antimicrobial Peptides in Combating Recurrent Urinary Tract Infections in Women (Chief Investigator). Wellcome Trust 2009-12: £202,626  ($330,000)

Publications

Peer Reviewed Papers

• Bladder-Drained Pancreas Transplantation: Urothelial Innate Defenses and Urinary Tract Infection Susceptibility. M Byrne, A Singh, CA Mowbray, PD Aldridge, LKL Drage, ASM Ali, L Bates, J Hall, Wilson C. J Surg Res. 2019; 235:288-297

• High molecular weight hyaluronic acid: a two-pronged protectant against infection of the urogenital tract? CA Mowbray, S Shams, G Chung, A Stanton, P Aldridge, A Suchenko, RS Pickard, AS Ali, Hall J. Clin Transl Immunology. 2018; 7(6):e1021

• Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat  Female Recurrent Urinary Tract Infection. ASM Ali, M Lanz, A Stanton, S Bowen, C Varley,  C Mowbray,   K Brown, WA Robson, J Southgate, P Aldridge, A Tyson-Capper, SN Abraham, J Hall, RS Pickard. Scientific Reports. 2017 8;7(1):11039.

• Mortality of emergency abdominal surgery in high-, middle- and low-income countries. GlobalSurg Collaborative. Br J Surg. 2016;103(8):971-988.

• Prostate Specific Antigen enhances the innate defence of prostatic epithelium against Escherichia coli infection. CL Townes, A Ali, N Gross, D Pal, S Williamson, R Heer, CN Robson, RS Pickard, J Hall. Prostate 2013; 73(14):1529-37.

• Hyperammonaemic encephalopathy secondary to an infected perinephric urinoma. N Vasdev, Mafield S AS Ali, Walton J, Walton K, DJ Thomas, RS Pickard and AC Thorpe. Journal of Clinical Urology 2013; 6(3): 191-193.

• The surgical management and prognosis of renal cell cancer with IVC tumor thrombus: 15-Years of experience using a multi-specialty approach at a single UK referral center. AS Ali, N Vasdev, S Shanmuganathan, E Paez, JH Dark, D Manas and DJ Thomas. Urol Oncol. 2013; 31(7): 1298-304.

• Current Status of Cryotherapy in Prostate Cancer. ASM Ali, H Smith, D Greene. British Journal of Medical and Surgical Urology 2012; 5S: S35–S38

• Tolerance of bacteruria after urinary diversion is linked to antimicrobial peptide activity. CL Townes, AS Ali, W Robson, RS Pickard and J Hall. Urology. 2011; 77(2): 509.e1-8.British Journal of Medical and Surgical Urology 2011; 4: 174-176.

• The Spectrum of Prostate Cancer Care – Curative Intent to Management to Palliation. ASM Ali and FC Hamdy. Current Urology Reports 2007; 8(3): 245-52.

• The Preoperative Embolization and Surgical Excision of an Intra-pericardial Phaeochromocytoma.  ASM Ali, M Devbhandari, A Shastri, RJ Ashleigh and MT Jones. The Annals of Thoracic Surgery 2007; 83(1):302.

• Chronic pancreatitis complicated by pancreaticopericardial fistula. SS Ching, ASM Ali, M Rao, S Yeluri, and MJ McMahon. Surgical Practice 2007; 11: 130–133.

• An unusual cystic lesion of the liver. M Rao, S Yeluri, A Ali, SS Ching and MJ McMahon. Gut 2006; 5: 742-742.

• Fatigability of the External Anal Sphincter in Anal Incontinence.  KJ Telford, ASM Ali, K Lymer, GL Hosker, ES Kiff and J Hill. Diseases of the Colon Rectum 2004; 47(5): 746-752.

• Concomitant gastric & biliary bypass with bilateral thoracoscopic splanchnotomy: the full package of minimally invasive palliation of pancreatic cancer. ASM Ali & BJ Ammori. Surg. Endosc 2003; 17(12): 2028-31.

• Detection of hTERT Protein by Flow Cytometry. ASM Ali, R Chopra, J Robertson and NG Testa. Leukemia 2000; 14(12): 2176-82.

Invited Book Chapters

• Lower Urinary Tract Infection chapter 176 and 178 in “Oxford Textbook of Clinical Nephrology (OTCN), Fourth Edition”, edited by Neil Turner,  David Goldsmith, Christopher Winearls, Norbert Lameire, Jonathan Himmelfarb, Christoph Wanner, Guiseppe Remuzzi, Oxford University Press, published October 2015, updated 2018.

• Pathogenesis of Urinary Tract Infection chapter 1.1 in “Oxford Textbook of Urological Surgery”, edited by Professor Freddie Hamdy and Mr Ian Eardley, Oxford University Press, published December 2017.